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IMSI Treatment Jodhpur

See Every Sperm Differently,
Choose Only the Best

IMSI is an advanced refinement of ICSI that allows sperm to be examined under very high magnification before selection.

At Galwa Care Hospital, Jodhpur, embryologists use IMSI in selected cases where sperm morphology, repeated failure or embryo quality needs closer assessment.

It supports more precise sperm selection and may improve fertilisation confidence in complex male infertility treatment.

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When Standard Selection Is Not Enough

When Is IMSI Needed?

IMSI is recommended in specific clinical situations where enhanced sperm selection under ultra-high
magnification is expected to meaningfully improve fertilization and embryo development outcomes.

Repeated IVF or ICSI Failures

When previous cycles have not resulted in successful fertilization or pregnancy despite good ovarian response, IMSI provides a significantly higher level of sperm selection precision to improve outcomes.

Severe Male Factor Infertility

High levels of abnormal sperm morphology or elevated DNA fragmentation where standard ICSI visual selection at conventional magnification is considered insufficient for reliable results.

Poor Embryo Quality

When embryos consistently show poor developmental grading in earlier cycles despite normal fertilization, suggesting that sperm quality at the structural level may be a contributing factor.

Recurrent Pregnancy Loss

Suspected sperm-related genetic or subtle structural issues contributing to repeated early pregnancy loss that standard semen analysis has not been able to fully identify or address.

Unexplained Fertility Issues

When no clearly identifiable cause is found but fertilization outcomes and embryo quality consistently remain suboptimal despite standard ICSI treatment in previous cycles.

Ultra-High Magnification, Superior Sperm Selection

The IMSI Procedure

IMSI follows the standard IVF and ICSI workflow with the critical addition of an ultra-high magnification sperm selection step that identifies the most structurally optimal sperm before injection.

Ovarian Stimulation

Hormonal medications are administered to the female partner over 10 to 14 days to stimulate the ovaries to produce multiple mature follicles, monitored closely through regular ultrasound scans.

Egg Retrieval (OPU)

Mature eggs are collected from the ovaries using an ultrasound-guided transvaginal aspiration procedure performed under mild sedation, typically taking 20 to 30 minutes.

Sperm Collection and Preparation

Required preparation, screening and safety checks are completed before sample collection or procedure planning.

Ultra-High Magnification Sperm Selection

Suitable options are reviewed carefully so selection remains safe, ethical and aligned with treatment needs.

Microinjection (IMSI)

The most structurally optimal sperm identified through ultra-high magnification is injected directly into each mature egg using the standard ICSI microinjection technique under high-powered microscopy.

Fertilization Monitoring

Eggs are carefully observed for successful fertilization over the following 16 to 18 hours, with fertilization confirmed by the appearance of two pronuclei in the successfully injected eggs.

Embryo Culture

Fertilized eggs are cultured under strictly controlled laboratory conditions for 3 to 5 days with daily developmental quality assessment by our experienced embryology team.

Embryo Transfer

The highest-quality embryo is transferred into the uterus using a thin, flexible catheter in a quick and painless procedure. Remaining good-quality embryos are cryopreserved for future use.

Pregnancy Test

A blood-based beta-hCG pregnancy test is conducted 10 to 14 days after embryo transfer to confirm whether successful implantation has occurred and pregnancy has been achieved.nn

Beyond What the Eye Can See

Benefits of IMSI Treatment

IMSI supports sharper sperm selection by identifying subtle defects that standard magnification may miss.

Improved Sperm Selection Accuracy

Ultra-high magnification reveals internal sperm defects that are entirely invisible under standard ICSI magnification, enabling far more precise and informed selection of the best sperm.

Higher Fertilization Success Rates

Selecting structurally superior sperm under magnified assessment improves the probability of successful fertilization compared to conventional ICSI sperm selection methods.

Better Embryo Quality and Development

Embryos created from morphologically optimal sperm selected through IMSI show improved cell division, developmental grading, and overall quality during the culture phase.

Reduced Risk of Genetic Abnormalities

By filtering out sperm with internal structural defects at ultra-high magnification, IMSI reduces the likelihood of chromosomal issues being present in the resulting embryo.

Valuable in Severe Male Infertility

IMSI is particularly beneficial when sperm quality is severely compromised and standard ICSI selection at conventional magnification is not sufficiently discriminating for reliable results.

Increased Chances After Repeated Failures

Couples with multiple failed IVF or ICSI cycles benefit from the added precision that ultra-high magnification sperm selection provides in subsequent treatment attempts.

Enhanced Implantation Potential

Higher-quality embryos resulting from IMSI selection are more likely to implant successfully in the uterine lining, improving the overall success rate of the transfer cycle.

May Reduce Early Pregnancy Loss

Improved embryo quality from IMSI selection may contribute meaningfully to reduced early pregnancy loss in cases where sperm quality issues have been a contributing factor.

More Precise than Conventional ICSI

IMSI represents the next level of sperm selection science, offering a significantly more refined approach for patients who have not achieved success with standard ICSI techniques.

Personalized for Maximum Clinical Benefit

IMSI is recommended selectively at Galwa Care Hospital for patients where its unique advantages in sperm selection are expected to deliver the greatest and most meaningful clinical benefit.nn

Every Detail Matters in Your Cycle

IMSI Treatment — Do's and Don'ts

Following these recommendations throughout your IMSI treatment cycle will protect sperm and egg quality, support optimal embryo development, and maximize your chances of a successful outcome.

DO'S — What You Should Do

Take all prescribed medications at the correct times and dosages as directed.

Attend all scheduled monitoring appointments throughout the treatment cycle.

Maintain a healthy, balanced diet rich in antioxidants, protein, and nutrients.

Stay well-hydrated by drinking adequate water throughout the stimulation phase.

Take prescribed prenatal vitamins including folic acid and omega-3 as advised.

Rest appropriately after both egg retrieval and embryo transfer procedures.

Communicate openly about any questions, symptoms, or concerns with your team.

Practice stress management techniques such as gentle exercise or meditation.

Follow all post-transfer instructions carefully including medication schedules.

Attend your pregnancy test and all follow-up appointments at recommended times.

DONT'S — What You Should Avoid

Do not skip or adjust medications without consulting your specialist first.

Avoid smoking completely throughout the cycle as it reduces sperm and egg quality.

Do not consume alcohol during the treatment cycle at any point whatsoever.

Avoid vigorous exercise and heavy lifting especially after retrieval and transfer.

Do not use hot tubs, saunas, or steam rooms as heat exposure harms eggs and sperm.

Avoid taking unprescribed supplements or herbal remedies without approval.

Do not consume excessive caffeine and keep to one small cup per day maximum.

Avoid processed foods, refined sugars, and trans fats throughout the cycle.

Do not take a pregnancy test before 14 days post-transfer as results are unreliable.

Do not lose hope after one failed cycle, discuss adjustments with your specialist.

Next-Generation Sperm Selection Technology

Precision Embryology at Every
Stage of Your Journey

Advanced IMSI technology with ultra-high magnification imaging up to 6000x

Highly skilled embryologists and experienced fertility specialists

Precision-based sperm selection for consistently improved clinical outcomes

Personalized IVF and IMSI protocols designed around each individual patient

High-quality laboratory infrastructure with strict safety and quality standards

Evidence-based fertility treatment approach throughout every stage of care

Integrated fertility solutions from consultation to pregnancy under one roof

2000+

Eggs Successfully Frozen

98%

Vitrification Survival Rate

15+

Years of Experience

24/7

Support to Call

Advanced Treatment, Transparent Pricing

How Much Does IMSI Treatment Cost?

IMSI treatment cost is determined by the overall IVF protocol and the specific clinical requirements of each couple. IMSI is offered as an advanced sperm selection add-on to a standard ICSI cycle. At Galwa Care Hospital, all pricing is communicated clearly and transparently upfront with no hidden charges.

Easy EMI Facility Available

Ovarian stimulation medications

Monitoring scans and blood tests

Egg retrieval procedure

Ultra-high magnification sperm selection

IMSI microinjection procedure

Embryo culture and grading

Embryo transfer and luteal support

Easy EMI Facility Available

Shape Image

IMSI Questions Clearly Answered

Frequently AskednQuestions.

IMSI (Intra Cytoplasmic Morphologically Selected Sperm Injection) is an advanced sperm selection technique used in IVF that examines sperm under ultra-high magnification of up to 6000x, far greater than conventional ICSI. This allows embryologists to detect subtle internal morphological defects in sperm that are entirely invisible under standard ICSI magnification. By selecting only structurally optimal sperm for injection, IMSI aims to improve fertilization quality, embryo development, and ultimately the overall success of the treatment cycle.

IMSI is most beneficial for patients with repeated IVF or ICSI failures, severe male factor infertility with high levels of abnormal morphology, recurrent pregnancy loss, or consistently poor embryo quality in previous cycles. It is not a routine requirement for all IVF patients and is recommended selectively at Galwa Care Hospital for cases where its unique advantages in precision sperm selection are expected to add the most meaningful clinical benefit. Your specialist will assess your individual profile and advise accordingly.

IMSI can meaningfully improve outcomes in specifically selected cases, particularly those involving severe male morphology issues or repeated treatment failures where standard ICSI selection has not been sufficient. Clinical evidence supports its benefit in these patient groups in terms of fertilization rates and embryo quality. IMSI may also help reduce miscarriage risk in cases where subtle sperm structural or DNA-related defects have been contributing to early pregnancy loss by ensuring only the most structurally sound sperm are used.

No. IMSI is performed entirely in the embryology laboratory and does not involve any additional procedure or discomfort for the patient beyond the standard IVF and ICSI cycle experience. The ultra-high magnification sperm selection step takes additional laboratory time compared to standard ICSI, but the overall treatment cycle timeline remains that of a standard IVF cycle, typically 2 to 3 weeks from ovarian stimulation to the pregnancy test result.

Yes on both counts. Frozen sperm that has been thawed and prepared in the laboratory can be used effectively in IMSI, as the ultra-high magnification selection process works equally well with thawed sperm samples. All surplus good-quality embryos produced during an IMSI cycle can be vitrified and stored securely at Galwa Care Hospital for future frozen embryo transfer cycles, improving the overall cumulative success potential and cost-efficiency of each treatment cycle undertaken.

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